Constitutive activation of a variant of the env-mpl oncogene product by disulfide-linked homodimerization.
The myeloproliferative leukemia retrovirus (MPLV) has the v-mpl cellular sequences transduced in frame with the deleted and rearranged Friend murine leukemia virus env gene. The resulting env-mpl fusion oncogene is responsible for an acute myeloproliferative disorder induced in mice by MPLV. v-mpl i...
Uloženo v:
| Vydáno v: | J Virol |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1995
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188973/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7707501/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.5.2794-2800.1995 |
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