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Constitutive activation of a variant of the env-mpl oncogene product by disulfide-linked homodimerization.

The myeloproliferative leukemia retrovirus (MPLV) has the v-mpl cellular sequences transduced in frame with the deleted and rearranged Friend murine leukemia virus env gene. The resulting env-mpl fusion oncogene is responsible for an acute myeloproliferative disorder induced in mice by MPLV. v-mpl i...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Courtois, G, Bénit, L, Mikaeloff, Y, Pauchard, M, Charon, M, Varlet, P, Gisselbrecht, S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188973/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7707501/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.5.2794-2800.1995
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