Constitutive activation of a variant of the env-mpl oncogene product by disulfide-linked homodimerization.

The myeloproliferative leukemia retrovirus (MPLV) has the v-mpl cellular sequences transduced in frame with the deleted and rearranged Friend murine leukemia virus env gene. The resulting env-mpl fusion oncogene is responsible for an acute myeloproliferative disorder induced in mice by MPLV. v-mpl i...

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Main Authors: Courtois, G, Bénit, L, Mikaeloff, Y, Pauchard, M, Charon, M, Varlet, P, Gisselbrecht, S
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC188973/
https://ncbi.nlm.nih.gov/pubmed/7707501
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