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Deep sequencing reveals double mutations in cis of MPL exon 10 in myeloproliferative neoplasms

Somatic mutations of MPL exon 10, mainly involving a W515 substitution, have been described in JAK2 (V617F)-negative patients with essential thrombocythemia and primary myelofibrosis. We used direct sequencing and high-resolution melt analysis to identify mutations of MPL exon 10 in 570 patients wit...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Daniela Pietra, Angela Brisci, Elisa Rumi, Sabrina Boggi, Chiara Elena, Alessandro Pietrelli, Roberta Bordoni, Maurizio Ferrari, Francesco Passamonti, Gianluca De Bellis, Laura Cremonesi, Mario Cazzola
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Ferrata Storti Foundation 2011-04-01
Rangatū:Haematologica
Urunga tuihono:https://haematologica.org/article/view/5941
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