Deep sequencing reveals double mutations in cis of MPL exon 10 in myeloproliferative neoplasms

Somatic mutations of MPL exon 10, mainly involving a W515 substitution, have been described in JAK2 (V617F)-negative patients with essential thrombocythemia and primary myelofibrosis. We used direct sequencing and high-resolution melt analysis to identify mutations of MPL exon 10 in 570 patients wit...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Daniela Pietra, Angela Brisci, Elisa Rumi, Sabrina Boggi, Chiara Elena, Alessandro Pietrelli, Roberta Bordoni, Maurizio Ferrari, Francesco Passamonti, Gianluca De Bellis, Laura Cremonesi, Mario Cazzola
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Ferrata Storti Foundation 2011-04-01
Edice:	Haematologica
On-line přístup:	https://haematologica.org/article/view/5941
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!