Constitutive activation of a variant of the env-mpl oncogene product by disulfide-linked homodimerization.

The myeloproliferative leukemia retrovirus (MPLV) has the v-mpl cellular sequences transduced in frame with the deleted and rearranged Friend murine leukemia virus env gene. The resulting env-mpl fusion oncogene is responsible for an acute myeloproliferative disorder induced in mice by MPLV. v-mpl i...

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Bibliographic Details
Main Authors: Courtois, G, Bénit, L, Mikaeloff, Y, Pauchard, M, Charon, M, Varlet, P, Gisselbrecht, S
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC188973/
https://ncbi.nlm.nih.gov/pubmed/7707501
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