LMP-1 activates NF-kappa B by targeting the inhibitory molecule I kappa B alpha.

LMP-1, an Epstein-Barr virus membrane protein expressed during latent infection, has oncogenic properties, as judged from its ability to transform B lymphocytes and rodent fibroblasts. LMP-1 induces the expression of bcl2, an oncogene which protects cells from apoptosis, as well as of genes encoding...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Herrero, J A, Mathew, P, Paya, C V
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188885/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7884865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2168-2174.1995
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