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LMP-1 activates NF-kappa B by targeting the inhibitory molecule I kappa B alpha.

LMP-1, an Epstein-Barr virus membrane protein expressed during latent infection, has oncogenic properties, as judged from its ability to transform B lymphocytes and rodent fibroblasts. LMP-1 induces the expression of bcl2, an oncogene which protects cells from apoptosis, as well as of genes encoding...

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Bibliografiske detaljer
Main Authors: Herrero, J A, Mathew, P, Paya, C V
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC188885/
https://ncbi.nlm.nih.gov/pubmed/7884865
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