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Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B.

NF-kappa B is an important activator of immune and inflammatory response genes. NF-kappa B is sequestered in the cytoplasm of nonstimulated cells through interaction with the I kappa B inhibitors. These inactive complexes are dissociated in response to a variety of extracellular signals, thereby all...

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Библиографические подробности
Главные авторы: DiDonato, J A, Mercurio, F, Karin, M
Формат: Artigo
Язык:Inglês
Опубликовано: 1995
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC230353/
https://ncbi.nlm.nih.gov/pubmed/7862124
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