Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B.
NF-kappa B is an important activator of immune and inflammatory response genes. NF-kappa B is sequestered in the cytoplasm of nonstimulated cells through interaction with the I kappa B inhibitors. These inactive complexes are dissociated in response to a variety of extracellular signals, thereby all...
Uloženo v:
| Vydáno v: | Mol Cell Biol |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
1995
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230353/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862124/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.3.1302 |
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