LMP-1 activates NF-kappa B by targeting the inhibitory molecule I kappa B alpha.
LMP-1, an Epstein-Barr virus membrane protein expressed during latent infection, has oncogenic properties, as judged from its ability to transform B lymphocytes and rodent fibroblasts. LMP-1 induces the expression of bcl2, an oncogene which protects cells from apoptosis, as well as of genes encoding...
Spremljeno u:
| Izdano u: | J Virol |
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| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
1995
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188885/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7884865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.4.2168-2174.1995 |
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