Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha.
The NK-kappa B transcription factor complex is sequestered in the cytoplasm by the inhibitory protein I kappa B-alpha (MAD-3). Various cellular stimuli relieve this inhibition by mechanisms largely unknown, leading to NF-kappa B nuclear localization and transactivation of its target genes. It is dem...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46122/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8460169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.6.2532 |
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