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PtdIns(3,4,5)P(3)-Dependent and -Independent Roles for PTEN in the Control of Cell Migration
BACKGROUND: Phosphatase and tensin homolog (PTEN) mediates many of its effects on proliferation, growth, survival, and migration through its PtdIns(3,4,5)P(3) lipid phosphatase activity, suppressing phosphoinositide 3-kinase (PI3K)-dependent signaling pathways. PTEN also possesses a protein phosphat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885949/ https://ncbi.nlm.nih.gov/pubmed/17240336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2006.12.026 |
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