Physiological Expression of the Gene for PrP-Like Protein, PrPLP/Dpl, by Brain Endothelial Cells and its Ectopic Expression in Neurons of PrP-Deficient Mice Ataxic Due to Purkinje Cell Degeneration

Recently, a novel gene encoding a prion protein (PrP)-like glycoprotein, PrPLP/Dpl, was identified as being expressed ectopically by neurons of the ataxic PrP-deficient (Prnp(−/−)) mouse lines exhibiting Purkinje cell degeneration. In adult wild-type mice, PrPLP/Dpl mRNA was physiologically expresse...

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Bibliographische Detailangaben
Hauptverfasser: Li, Aimin, Sakaguchi, Suehiro, Shigematsu, Kazuto, Atarashi, Ryuichiro, Roy, Bhabesh C., Nakaoke, Ryota, Arima, Kazuhiko, Okimura, Nobuhiko, Kopacek, Juraj, Katamine, Shigeru
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2000
Schlagworte:
Short Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885740/
https://ncbi.nlm.nih.gov/pubmed/11073804
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