Ataxia with Cerebellar Lesions in Mice Expressing Chimeric PrP-Dpl Protein

Mutations within the central region of prion protein (PrP) have been shown to be associated with severe neurotoxic activity similar to that observed with Dpl, a PrP-like protein. To further investigate this neurotoxic effect, we generated lines of transgenic (Tg) mice expressing three different chim...

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Publicado en:J Neurosci
Autores principales: Lemaire-Vieille, Catherine, Bailly, Yannick, Erlich, Paul, Loeuillet, Corinne, Brocard, Jacques, Haeberlé, Anne-Marie, Bombarde, Guy, Rak, Camille, Demais, Valérie, Dumestre-Pérard, Chantal, Gagnon, Jean, Cesbron, Jean-Yves
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2013
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618747/
https://ncbi.nlm.nih.gov/pubmed/23345215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2231-12.2013
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