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Complement Protein C1q Forms a Complex with Cytotoxic Prion Protein Oligomers

A growing number of studies have investigated the interaction between C1q and PrP, but the oligomeric form of PrP involved in this interaction remains to be determined. Aggregation of recombinant full-length murine PrP in the presence of 100 mm NaCl allowed us to isolate three different types of oli...

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Autors principals: Erlich, Paul, Dumestre-Pérard, Chantal, Ling, Wai Li, Lemaire-Vieille, Catherine, Schoehn, Guy, Arlaud, Gérard J., Thielens, Nicole M., Gagnon, Jean, Cesbron, Jean-Yves
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885205/
https://ncbi.nlm.nih.gov/pubmed/20410306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.071860
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