Complement System and Alarmin HMGB1 Crosstalk: For Better or Worse

Our immune system responds to infectious (PAMPs) and tissue damage (DAMPs) signals. The complement system and alarmin High-Mobility Group Box 1 (HMGB1) are two powerful soluble actors of human host defense and immune surveillance. These systems involve molecular cascades and amplification loops for...

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Autores principales: Christine Gaboriaud, Marie Lorvellec, Véronique Rossi, Chantal Dumestre-Pérard, Nicole M. Thielens
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2022-04-01
Colección:Frontiers in Immunology
Materias:
complement system
interplay
HMGB1
auto-immunity
lupus
inflammation
Acceso en línea:https://www.frontiersin.org/articles/10.3389/fimmu.2022.869720/full
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