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The Volumetric Diversity of Misfolded Prion Protein Oligomers Revealed by Pressure Dissociation
Protein oligomerization has been associated with a wide range of diseases. High pressure approaches offer a powerful tool for deciphering the underlying molecular mechanisms by revealing volume changes associated with the misfolding and assembly reactions. We applied high pressure to induce conforma...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536447/ https://ncbi.nlm.nih.gov/pubmed/26126829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.661710 |
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