Upregulation of the Genes Encoding Lysosomal Hydrolases, a Perforin-Like Protein, and Peroxidases in the Brains of Mice Affected with an Experimental Prion Disease

In an attempt to identify the molecules involved in the pathogenesis of prion diseases, we performed cDNA subtraction on the brain tissues of mice affected with an experimental prion disease and the unaffected control. The genes identified as being upregulated in the prion-affected brain tissue incl...

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Main Authors: Kopacek, Juraj, Sakaguchi, Suehiro, Shigematsu, Kazuto, Nishida, Noriyuki, Atarashi, Ryuichirou, Nakaoke, Ryota, Moriuchi, Ryozo, Niwa, Masami, Katamine, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC111552/
https://ncbi.nlm.nih.gov/pubmed/10590130
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