The human checkpoint sensor Rad9–Rad1–Hus1 interacts with and stimulates NEIL1 glycosylase

The checkpoint protein Rad9/Rad1/Hus1 heterotrimer (the 9-1-1 complex) is structurally similar to the proliferating cell nuclear antigen sliding clamp and has been proposed to sense DNA damage that leads to cell cycle arrest or apoptosis. Human (h) NEIL1 DNA glycosylase, an ortholog of bacterial Nei...

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Hlavní autoři: Guan, Xin, Bai, Haibo, Shi, Guoli, Theriot, Corey A., Hazra, Tapas K., Mitra, Sankar, Lu, A-Lien
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2007
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885643/
https://ncbi.nlm.nih.gov/pubmed/17395641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm075
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