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The human checkpoint sensor Rad9–Rad1–Hus1 interacts with and stimulates NEIL1 glycosylase

The checkpoint protein Rad9/Rad1/Hus1 heterotrimer (the 9-1-1 complex) is structurally similar to the proliferating cell nuclear antigen sliding clamp and has been proposed to sense DNA damage that leads to cell cycle arrest or apoptosis. Human (h) NEIL1 DNA glycosylase, an ortholog of bacterial Nei...

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Detalhes bibliográficos
Main Authors: Guan, Xin, Bai, Haibo, Shi, Guoli, Theriot, Corey A., Hazra, Tapas K., Mitra, Sankar, Lu, A-Lien
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885643/
https://ncbi.nlm.nih.gov/pubmed/17395641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm075
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