SIRT6 protein deacetylase interacts with MYH DNA glycosylase, APE1 endonuclease, and Rad9–Rad1–Hus1 checkpoint clamp

BACKGROUND: SIRT6, a member of the NAD(+)-dependent histone/protein deacetylase family, regulates genomic stability, metabolism, and lifespan. MYH glycosylase and APE1 are two base excision repair (BER) enzymes involved in mutation avoidance from oxidative DNA damage. Rad9–Rad1–Hus1 (9–1–1) checkpoi...

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Detalhes bibliográficos
Publicado no:BMC Mol Biol
Main Authors: Hwang, Bor-Jang, Jin, Jin, Gao, Ying, Shi, Guoli, Madabushi, Amrita, Yan, Austin, Guan, Xin, Zalzman, Michal, Nakajima, Satoshi, Lan, Li, Lu, A-Lien
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464616/
https://ncbi.nlm.nih.gov/pubmed/26063178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-015-0041-9
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