Alphavirus Replicon Approach to Promoterless Analysis of IRES Elements

Here we describe a system for promoterless analysis of putative internal ribosome entry site (IRES) elements using an alphavirus (Family Togaviridae) replicon vector. The system uses the alphavirus subgenomic promoter to produce transcripts that, when modified to contain a spacer region upstream of...

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Main Authors: Kamrud, K.I., Custer, M., Dudek, J.M., Owens, G., Alterson, K.D., Lee, J.S., Groebner, J.L., Smith, J.F.
格式: Artigo
語言:Inglês
出版: 2006
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885372/
https://ncbi.nlm.nih.gov/pubmed/17156813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.10.049
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