In Vitro and In Vivo Characterization of MicroRNA-Targeted Alphavirus Replicon and Helper RNAs

Alphavirus-based replicon vector systems (family Togaviridae) have been developed as expression vectors with demonstrated potential in vaccine development against both infectious diseases and cancer. The single-cycle nature of virus-like replicon particles (VRP), generated by supplying the structura...

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Main Authors: Kamrud, Kurt I., Coffield, V. McNeil, Owens, Gary, Goodman, Christin, Alterson, Kim, Custer, Max, Murphy, Michael A., Lewis, Whitney, Timberlake, Sarah, Wansley, Elizabeth K., Berglund, Peter, Smith, Jonathan
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
主題:
Vaccines and Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897628/
https://ncbi.nlm.nih.gov/pubmed/20504925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00310-10
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