Molecular Smallpox Vaccine Delivered by Alphavirus Replicons Elicits Protective Immunity in Mice and Non-human Primates

Naturally occurring smallpox was eradicated as a result of successful vaccination campaigns during the 1960s and 70s. Because of its highly contagious nature and high mortality rate, smallpox has significant potential as a biological weapon. Unfortunately, the current vaccine for orthopoxviruses is...

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Main Authors: Hooper, Jay W., Ferro, Anthony M., Golden, Joseph W., Silvera, Peter, Dudek, Jeanne, Alterson, Kim, Custer, Max, Rivers, Bryan, Morris, John, Owens, Gary, Smith, Jonathan F., Kamrud, Kurt I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789203/
https://ncbi.nlm.nih.gov/pubmed/19833247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.09.133
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