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Development and characterization of promoterless helper RNAs for the production of alphavirus replicon particle

Alphavirus-based replicon systems are frequently used as preclinical vectors and as antigen discovery tools, and they have recently been assessed in clinical vaccine trials. Typically, alphavirus replicon RNAs are delivered within virus-like replicon particles (VRP) that are produced following trans...

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Detalhes bibliográficos
Main Authors: Kamrud, K. I., Alterson, K., Custer, M., Dudek, J., Goodman, C., Owens, G., Smith, J. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888770/
https://ncbi.nlm.nih.gov/pubmed/20181749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.020081-0
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