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Venezuelan Equine Encephalitis Replicon Particles Can Induce Rapid Protection against Foot-and-Mouth Disease Virus

We have previously shown that delivery of the porcine type I interferon gene (poIFN-α/β) with a replication-defective human adenovirus vector (adenovirus 5 [Ad5]) can sterilely protect swine challenged with foot-and-mouth disease virus (FMDV) 1 day later. However, the need of relatively high doses o...

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Main Authors: Diaz-San Segundo, Fayna, Dias, Camila C. A., Moraes, Mauro P., Weiss, Marcelo, Perez-Martin, Eva, Owens, Gary, Custer, Max, Kamrud, Kurt, de los Santos, Teresa, Grubman, Marvin J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648198/
https://ncbi.nlm.nih.gov/pubmed/23468490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03462-12
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