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Assessment of the validity of a population pharmacokinetic model for epirubicin
AIMS: The aim of this study was to evaluate a population model for epirubicin clearance using internal and external validation techniques. METHODS: Jackknife samples were used to identify outliers in the population dataset and individuals influencing covariate selection. Sensitivity analyses were pe...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Blackwell Science Inc
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885074/ https://ncbi.nlm.nih.gov/pubmed/16842378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02584.x |
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