Clinical pharmacokinetics of epirubicin: the importance of liver biochemistry tests.

The influence of liver biochemistry tests on epirubicin pharmacokinetics has been investigated in 52 women with advanced breast cancer, 27 of whom had radiologically proven liver metastases. Patients received epirubicin 12.5-120 mg m-2 given as an i.v. bolus. Epirubicin levels were measured by HPLC...

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Main Authors: Twelves, C. J., Dobbs, N. A., Michael, Y., Summers, L. A., Gregory, W., Harper, P. G., Rubens, R. D., Richards, M. A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1992
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977407/
https://ncbi.nlm.nih.gov/pubmed/1419619
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