Maximum a posteriori Bayesian estimation of epirubicin clearance by limited sampling

AIMS: To develop a limited sampling strategy for estimation of epirubicin clearance. METHODS: The data set comprised 1051 concentrations measured in 105 patients with advanced or metastatic breast cancer treated with epirubicin alone. Ten limited sampling designs comprising two or three blood sample...

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Autores principales: Ralph, Lorraine D, Thomson, Alison H, Dobbs, Nicola A, Twelves, Chris
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2004
Materias:
Pharmacokinetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884520/
https://ncbi.nlm.nih.gov/pubmed/15151522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02084.x
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