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Models for time-varying covariates in population pharmacokinetic-pharmacodynamic analysis
AIM: If appropriately accounted for in a pharmacokinetic (PK)–pharmacodynamic (PD) model, time-varying covariates can provide additional information to that obtained from time-constant covariates. The aim was to present and apply two models applicable to time-varying covariates that capture such add...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1884602/ https://ncbi.nlm.nih.gov/pubmed/15373929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02170.x |
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