Population pharmacokinetics and association between A77 1726 plasma concentrations and disease activity measures following administration of leflunomide to people with rheumatoid arthritis

AIMS: To investigate the concentration-effect relationship and pharmacokinetics of leflunomide in patients with rheumatoid arthritis (RA). METHODS: Data were collected from 23 RA patients on leflunomide therapy (as sole disease modifying antirheumatic drug (DMARD)) for at least 3 months. Main measur...

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Bibliographische Detailangaben
Hauptverfasser: Chan, Vivien, Charles, Bruce G, Tett, Susan E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2005
Schlagworte:
Pharmacokinetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884779/
https://ncbi.nlm.nih.gov/pubmed/16120064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02415.x
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