Pharmacokinetics and renal excretion of desmopressin after intravenous administration to healthy subjects and renally impaired patients

OBJECTIVE: To evaluate the influence of renal impairment on the pharmacokinetics of desmopressin. METHODS: Twenty-four subjects were enrolled in the study, 18 with varying degrees of renal impairment and six healthy volunteers. Each subject received a single intravenous dose of 2 µg desmopressin. Bl...

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Detalhes bibliográficos
Main Authors: Agersø, Henrik, Seiding Larsen, Lotte, Riis, Anders, Lövgren, Ulf, Karlsson, Mats O, Senderovitz, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884604/
https://ncbi.nlm.nih.gov/pubmed/15373927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02175.x
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