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Metabolism, Excretion, and Pharmacokinetics of [(14)C]‐Cefiderocol (S‐649266), a Siderophore Cephalosporin, in Healthy Subjects Following Intravenous Administration

The objectives of this study were to characterize the concentration‐time profiles of total radioactivity equivalent and unchanged cefiderocol, the route(s) of elimination and mass balance, and safety of cefiderocol after intravenous administration of a single 1000‐mg (100 μCi) dose of [(14)C]‐cefide...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: Miyazaki, Shiro, Katsube, Takayuki, Shen, Helen, Tomek, Charles, Narukawa, Yukitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593826/
https://ncbi.nlm.nih.gov/pubmed/30730562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1386
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