Cefiderocol, a Siderophore Cephalosporin for Gram‐Negative Bacterial Infections: Pharmacokinetics and Safety in Subjects With Renal Impairment

Cefiderocol, a new injectable siderophore cephalosporin antibiotic, has promising in vitro and in vivo activity against Gram‐negative bacteria including multidrug‐resistant Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. Cefiderocol is mainly renally eliminated. The pharm...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: Katsube, Takayuki, Echols, Roger, Arjona Ferreira, Juan Camilo, Krenz, Heidi K., Berg, Jolene Kay, Galloway, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Special Populations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412848/
https://ncbi.nlm.nih.gov/pubmed/27874971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.841
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