Population Pharmacokinetic Analysis of Cefiderocol, a Parenteral Siderophore Cephalosporin, in Healthy Subjects, Subjects with Various Degrees of Renal Function, and Patients with Complicated Urinary Tract Infection or Acute Uncomplicated Pyelonephritis

Cefiderocol, a novel parenteral siderophore cephalosporin, exhibits potent efficacy against most Gram-negative bacteria, including carbapenem-resistant strains. The aim of this study was to perform a population pharmacokinetic (PK) analysis based on plasma cefiderocol concentrations in healthy subje...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kawaguchi, Nao, Katsube, Takayuki, Echols, Roger, Wajima, Toshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786804/
https://ncbi.nlm.nih.gov/pubmed/29038272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01391-17
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