A population pharmacokinetic model for cefuroxime using cystatin C as a marker of renal function

AIMS: Since cefuroxime mainly is excreted by renal filtration, dosing is currently based on serum creatinine (Scr) or creatinine clearance (CLcr). However, it has been suggested that cystatin C (CysC) is superior to Scr as a marker of renal function. The aim of this prospective study was to develop...

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Bibliographic Details
Main Authors: Viberg, Anders, Lannergård, Anders, Larsson, Anders, Cars, Otto, Karlsson, Mats O, Sandström, Marie
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2006
Subjects:
Pharmacokinetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885139/
https://ncbi.nlm.nih.gov/pubmed/16934045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02652.x
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