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Developmental pharmacokinetics of ciclosporin – a population pharmacokinetic study in paediatric renal transplant candidates
AIMS: To use population pharmacokinetic modelling to characterize the influence of developmental and demographic factors on the pharmacokinetic variability of ciclosporin. METHODS: Pharmacokinetic modelling was performed in NONMEM using a dataset comprising 162 pretransplant children, aged 0.36–17.5...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2198781/ https://ncbi.nlm.nih.gov/pubmed/17662086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.03003.x |
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