A time-to-event model for acute rejections in paediatric renal transplant recipients treated with ciclosporin A

AIMS: Ciclosporin A (CsA) dosing in immunosuppression after paediatric kidney transplantation remains challenging, and appropriate target CsA exposures (AUCs) are controversial. This study aimed to develop a time-to-first-acute rejection (AR) model and to explore predictive factors for therapy outco...

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Bibliographische Detailangaben
Hauptverfasser: Frobel, Anne-Kristina, Karlsson, Mats O, Backman, Janne T, Hoppu, Kalle, Qvist, Erik, Seikku, Paula, Jalanko, Hannu, Holmberg, Christer, Keizer, Ron J, Fanta, Samuel, Jönsson, Siv
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2013
Schlagworte:
Paediatric Clinical Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791983/
https://ncbi.nlm.nih.gov/pubmed/23521314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12121
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