Developmental pharmacokinetics of ciclosporin – a population pharmacokinetic study in paediatric renal transplant candidates

AIMS: To use population pharmacokinetic modelling to characterize the influence of developmental and demographic factors on the pharmacokinetic variability of ciclosporin. METHODS: Pharmacokinetic modelling was performed in NONMEM using a dataset comprising 162 pretransplant children, aged 0.36–17.5...

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Bibliografiska uppgifter
Huvudupphovsmän: Fanta, S, Jönsson, S, Backman, J T, Karlsson, M O, Hoppu, K
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2007
Ämnen:
Pharmacokinetics in Renal Transplantation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2198781/
https://ncbi.nlm.nih.gov/pubmed/17662086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.03003.x
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