Steady-state pharmacokinetics and safety of donepezil HCl in subjects with moderately impaired renal function

AIMS: To characterize the pharmacokinetic, pharmacodynamic and safety profiles of donepezil in subjects with moderate renal impairment and matched healthy controls during single-dose and multiple-dose phases. METHODS: This open-label study enrolled subjects with moderate renal impairment (creatinine...

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Detalhes bibliográficos
Main Authors: Nagy, Christa F, Kumar, Dinesh, Cullen, Edward I, Bolton, W Kline, Marbury, Thomas C, Gutierrez, Maria J, Hutman, H Wayne, Pratt, Raymond D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
The clinical pharmacokinetics and safety of donepezil: an update Guest Editors: Stephen Jackson & Roy Jones
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884552/
https://ncbi.nlm.nih.gov/pubmed/15496219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.01803.x
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