Concurrent administration of donepezil HCl and risperidone in patients with schizophrenia: assessment of pharmacokinetic changes and safety following multiple oral doses

AIM: This open-label, multiple-dose trial investigated the effect of concurrent administration of donepezil HCl with risperidone on the pharmacokinetics (PK) and safety profiles of both drugs. METHODS: Sixteen male patients with schizophrenia, who were receiving stable, physician-optimized risperido...

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Detalhes bibliográficos
Main Authors: Reyes, Josephine F, Preskorn, Sheldon H, Khan, Ahsan, Kumar, Dinesh, Cullen, Edward I, Perdomo, Carlos A, Pratt, Raymond D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
The clinical pharmacokinetics and safety of donepezil: an update Guest Editors: Stephen Jackson & Roy Jones
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884550/
https://ncbi.nlm.nih.gov/pubmed/15496223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.01817.x
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