Pharmacokinetics and pharmacodynamics of terbogrel, a combined thromboxane A(2) receptor and synthase inhibitor, in healthy subjects

AIMS: To characterize the pharmacokinetics of terbogrel, a new combined thromboxane A(2) (TxA(2)) receptor and synthase inhibitor, in healthy human subjects after single or multiple oral administration. METHODS: Forty-eight healthy male subjects received a single oral dose (10, 25, 50, 100, 150 or 2...

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Detalhes bibliográficos
Main Authors: Guth, Brian D, Narjes, Hans, Schubert, Hans-Dieter, Tanswell, Paul, Riedel, Axel, Nehmiz, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Pharmacokinetics/Pharmacodynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884538/
https://ncbi.nlm.nih.gov/pubmed/15206991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02083.x
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