A discordance between cytochrome P450 2D6 genotype and phenotype in patients undergoing methadone maintenance treatment

AIMS: To assess CYP2D6 activity and genotype in a group of patients undergoing methadone maintenance treatment (MMT). METHODS: Blood samples from 34 MMT patients were genotyped by a polymerase chain reaction-based method, and results were compared with CYP2D6 phenotype (n = 28), as measured by the m...

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Detalhes bibliográficos
Main Authors: Shiran, M R, Chowdry, J, Rostami-Hodjegan, A, Ellis, S W, Lennard, M S, Iqbal, M Z, Lagundoye, O, Seivewright, N, Tucker, G T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884285/
https://ncbi.nlm.nih.gov/pubmed/12895196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01851.x
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