A discordance of the cytochrome P450 2C19 genotype and phenotype in patients with advanced cancer

AIMS: To examine the relationship between cytochrome P450 2C19 (CYP2C19) genotype and expressed metabolic activity in 16 patients with advanced metastatic cancer. METHODS: Individual CYP2C19 genotypes were determined by PCR-based amplification, followed by restriction fragment length analysis, and c...

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Detalhes bibliográficos
Main Authors: Williams, Marion L, Bhargava, Pankaj, Cherrouk, Ilham, Marshall, John L, Flockhart, David A, Wainer, Irving W
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Short Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014949/
https://ncbi.nlm.nih.gov/pubmed/10792207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00189.x
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