Influence of phenylalanine-481 substitutions on the catalytic activity of cytochrome P450 2D6.

Homology models of the active site of cytochrome P450 2D6 (CYP2D6) have identified phenylalanine 481 (Phe(481)) as a putative ligand-binding residue, its aromatic side chain being potentially capable of participating in pi-pi interactions with the benzene ring of ligands. We have tested this hypothe...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Hayhurst, G P, Harlow, J, Chowdry, J, Gross, E, Hilton, E, Lennard, M S, Tucker, G T, Ellis, S W
Médium: Artigo
Jazyk:Inglês
Vydáno: 2001
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221748/
https://ncbi.nlm.nih.gov/pubmed/11284724
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky