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Diabetes mellitus increases the in vivo activity of cytochrome P450 2E1 in humans

AIM: Cytochrome P450 2E1 (CYP2E1) is thought to activate a number of protoxins, and has been implicated in the development of liver disease. Increased hepatic expression of CYP2E1 occurs in rat models of diabetes but it is unclear whether human diabetics display a similar up-regulation. This study w...

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Main Authors: Wang, Zaiqi, Hall, Stephen D, Maya, Juan F, Li, Lang, Asghar, Ali, Gorski, J C
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884181/
https://ncbi.nlm.nih.gov/pubmed/12534643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01731.x
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