Comparison of inhibition of Escherichia coli topoisomerase IV by quinolones with DNA gyrase inhibition.

In order to examine the inhibitory activities of quinolones against topoisomerase IV, both subunits of this enzyme, ParC and ParE, were purified from Escherichia coli. The specific activity of topoisomerase IV decatenation was found to be more than five times greater than that of topoisomerase IV re...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Hoshino, K, Kitamura, A, Morrissey, I, Sato, K, Kato, J, Ikeda, H
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188252/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7872758/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.11.2623
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