Quinolone resistance locus nfxD of Escherichia coli is a mutant allele of the parE gene encoding a subunit of topoisomerase IV.

The locus nfxD, which contributes to high-level quinolone resistance in Escherichia coli KF111b (gyrAr nfxB nfxD), is only expressed in the presence of a gyrA mutation, and maps to the region of the parC and parE genes, was outcrossed into strain KF130, creating strain DH161 (gyrAr nfxD). DNA sequen...

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Bibliographische Detailangaben
Hauptverfasser: Breines, D M, Ouabdesselam, S, Ng, E Y, Tankovic, J, Shah, S, Soussy, C J, Hooper, D C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC163680/
https://ncbi.nlm.nih.gov/pubmed/8980775
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