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Detection of mutations in parC in quinolone-resistant clinical isolates of Escherichia coli.

The gene parC encodes the A subunit of topoisomerase IV of Escherichia coli. Mutations in the parC region analogous to those in the quinolone resistance-determining region of gyrA were investigated in 27 clinical isolates of E. coli for which ciprofloxacin MICs were 0.0007 to 128 micrograms/ml. Of 1...

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Bibliografiska uppgifter
Huvudupphovsmän: Vila, J, Ruiz, J, Goñi, P, De Anta, M T
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1996
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC163143/
https://ncbi.nlm.nih.gov/pubmed/8834907
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