Detection of mutations in parC in quinolone-resistant clinical isolates of Escherichia coli.

The gene parC encodes the A subunit of topoisomerase IV of Escherichia coli. Mutations in the parC region analogous to those in the quinolone resistance-determining region of gyrA were investigated in 27 clinical isolates of E. coli for which ciprofloxacin MICs were 0.0007 to 128 micrograms/ml. Of 1...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Vila, J, Ruiz, J, Goñi, P, De Anta, M T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163143/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8834907/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.2.491
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